Researchers have developed a new way to deliver molecules that target specific genes within cells. Their platform, which uses a modified form of diphtheria toxin, has been shown to downregulate critical genes in cancer cells, and could be used for other genetic diseases as well
Researchers have developed a method to genetically reprogram cells to build artificial structures
New method for delivering DNA into stem cells and immune cells safely, rapidly and economically
Researchers are interfacing chemical biology and nanotechnology to develop ultrasound-controlled nanomaterials that can provide on-demand, high precision delivery of proteins into human cells
Researchers have now developed a method to rapidly and efficiently identify designer adeno-associated virus (AAV) variants that can deliver to or “transduce” specific types of cells in mice, enabling scientists to choose a virus based on research or clinical needs
Researchers developed an improved pluripotent stem cell differentiation protocol to generate beta cells in vitro with superior glucose response and insulin secretion. This is a major step towards beta cell replacement therapy
CRISPR corrects genetic defect so cells can normalize blood sugar
Researchers discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly. Using the CRISPR/Cas9 gene editing, they have also managed to modify the cells so that they can hide from the immune system to prevent rejection
The aim is to repair the error in the DNA without cutting it. This theoretically makes it a safer form of genetic editing. Scientists have shown for the first time that this technique can effectively and safely repair the DNA of stem cells derived from cystic fibrosis patients in the lab
